River Cruises from Ho Chi Minh City to Siem Reap
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10 best River cruises from Ho Chi Minh City to Siem Reap
Compiled by
MelissaHo Chi Minh City travel expert at TourRadar
- Wonders of Vietnam, Cambodia & the Mekong 2025|2026
- Fascinating Vietnam, Cambodia & the Mekong River (Northbound) 2025
- Charms of the Mekong 2027
- The Mekong in a different way - Between adventure and must-see sites (port-to-port cruise) (from Ho Chi Minh City to Siem Reap)
- The Mekong in a different way - Between adventure and must-seesites (13 destinations)
- From the Mekong Delta to the Angkor Temples (port-to-port cruise) (including Cai Be)
- From the Mekong Delta to Siem Reap (port-to-port cruise)
- Essential Vietnam and Cambodia Ho Chi Minh City to Siem Reap (2025)
- Majestic Mekong Cruise Ho Chi Minh City → Siem Reap (2025)
- The Mekong in a different way - Between adventure and must-seesites (10 destinations)
Setting out from Ho Chi Minh City's District 1, this 9-night cruise aboard Emerald Harmony navigates the Mekong Delta. The route passes through Sa Dec's markets and My An Hung's pepper farms, culminating at Siem Reap's UNESCO-listed Angkor temples with stays at the boutique Shinta Mani.
Duration 15 days Destinations Ho Chi Minh City, Cu Chi, Mekong Delta, Ben Tre, Sa Dec, My An Hung, Tan Chau, Phnom Penh, Koh Oknha Tei, Angkor BanSee all destinations Age Range up to 90 year olds Operator Emerald Cruises From $10,150
46% Off- US$5,493You save $4,657
A 7-night sailing aboard Avalon Saigon takes you from Ho Chi Minh City through Vietnam's Mekong Delta to Cambodia. The route includes Vinh Long's traditional workshops and Phnom Penh's Silver Pagoda, finishing in Siem Reap near the ancient Angkor Wat temple complex.
Duration 13 days Destinations Ho Chi Minh City, Vinh Long, Cu Lao Gieng, Chau Doc, Long Khanh, Phnom Penh, Hanchey, Angkor Ban, Kampong Tralach, Siem Reap Age Range 8 to 99 year olds Operator Avalon Waterways From
46% Off- US$6,339+$150 upfront costs
The voyage starts at Ho Chi Minh City's Sofitel Saigon Plaza, taking guests to Siem Reap across 8 days. The route winds through My Tho Port, Sa Dec's markets, and Cambodia's Silk Island aboard AmaDara, ending at Sofitel Angkor hotel with transfers included.
Duration 8 days Destinations Ho Chi Minh City, My Tho, Mekong Delta, Cai Be, Sa Dec, Tan Chau, Phnom Penh, Oudong, Kampong Tralach, Silk IslandSee all destinations Age Range up to 90 year olds Operator AmaWaterways From
46% Off- US$2,799
Your adventure starts in Ho Chi Minh City with French colonial sites and Chinatown, followed by a northward cruise through the Mekong Delta. Highlights include Cai Be's floating markets, Phnom Penh's Royal Palace, and Siem Reap after visiting Kampong Chhnang's fishing villages and Udong's ancient temples.
Duration 9 days Destinations Ho Chi Minh City, Cai Be, Sa Dec, Chau Doc, Phnom Penh, Kampong Tralach, Koh Chen, Siem Reap Age Range up to 99 year olds Operator CroisiEurope River Cruises From
46% Off- US$1,887
From Ho Chi Minh City's Giac Lam Pagoda, this route covers 13 destinations en route to Siem Reap. The itinerary features Mekong Delta's canals, Tra Su Forest boat rides, and cable cars to Sam Mountain, with a final 5-6 hour transfer to Lotus Blanc Hotel in Siem Reap.
Duration 9 days Destinations Ho Chi Minh City, My Tho, Thoi Son Island, Mekong Delta, Cai Be, Sa Dec, Chau Doc, Vinh Xuong, Phnom Penh, Koh ChenSee all destinations Age Range up to 99 year olds Operator CroisiEurope River Cruises From
46% Off- US$1,896
From the Mekong Delta to the Angkor Temples (port-to-port cruise) (including Cai Be)
2 Reviews by TourRadar travelers“Great experience will recommend.”
William, traveled in September 2019
Your trip starts in Ho Chi Minh City, featuring French colonial architecture and Cu Chi tunnels before sailing to Siem Reap via the Mekong Delta. The 2,700-mile route through Vietnam and Cambodia aboard RV Indochine II covers 12 destinations over 11 days.
Duration 11 days Destinations Ho Chi Minh City, My Tho, Vinh Long, Cai Be, Sa Dec, Chau Doc, Phnom Penh, Koh Chen, Kampong Tralach, Tonle Sap LakeSee all destinations Age Range up to 99 year olds Operator CroisiEurope River Cruises From
46% Off- US$3,259
From Ho Chi Minh City's Ba Thien Hau Pagoda and Cu Chi tunnels, the route continues through My Tho and Chau Doc to Siem Reap. This 2,700-mile voyage aboard vessels like RV Indochine II offers colonial-style comfort and expert guides throughout.
Duration 9 days Destinations Ho Chi Minh City, My Tho, Vinh Long, Cai Be, Sa Dec, Chau Doc, Phnom Penh, Koh Chen, Kampong Tralach, Tonle Sap LakeSee all destinations Age Range up to 99 year olds Operator CroisiEurope River Cruises From
46% Off- US$2,078
A 12-day route from Ho Chi Minh City to Siem Reap aboard RV Apsara takes in Mekong Delta's floating markets and Phnom Penh's Royal Palace, concluding at UNESCO-listed Angkor Wat. Guests stay at Le Meridien Saigon and Shinta Mani Angkor.
Duration 12 days Destinations Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Phnom Penh, Oudong, Koh Chen, Kampong Cham, Siem Reap Age Range up to 99 year olds Operator APT From
46% Off- US$2,978
An 8-day sailing from Ho Chi Minh City to Siem Reap aboard RV Apsara showcases Cai Be's historic church, Sa Dec's markets, and Phnom Penh's Royal Palace. Traditional village life in Angkor Ban precedes the final stop in temple-rich Siem Reap.
Duration 8 days Destinations Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Mekong Delta, Phnom Penh, Oudong, Koh Chen, Angkor BanSee all destinations Age Range up to 99 year olds Operator Travel Marvel From
46% Off- US$1,806
The Mekong in a different way - Between adventure and must-seesites (10 destinations)
2 Reviews by TourRadar travelers
Your adventure from Ho Chi Minh City includes Giac Lam Pagoda and Reunification Palace, continuing through Chao Gao canal to My Tho. The 11-day voyage aboard intimate Toum Tiou 2 covers 10 destinations before concluding in Siem Reap at the Angkor temples.
Duration 11 days Destinations Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Chau Doc, Phnom Penh, Oudong, Kampong Tralach, Koh Chen, Siem Reap Age Range up to 99 year olds Operator CroisiEurope River Cruises From
46% Off- US$2,476
