Greece and Italy Tours in September 2025
4.5 stars on(7,100 reviews)- Choose from 29 Greece and Italy tours
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10 best Greece and Italy trips in September 2025
Compiled by
NadineGreece and Italy travel expert at TourRadar
- Rome, Puglia, Meteoras and Greek Islands (13 destinations)
- Italy and Greece 4 Star w/Catamaran in Santorini
- Complete Greece and Sicily (43 destinations)
- Best of Italy and Greece with 3-day cruise
- Athens, Peninsula and Sicily End Rome (25 destinations)
- Italy and Greece Highlights with Island Hopping
- Best of Italy and Greece (14 Days)
- Italy and Santorini
- Best of Italy and Greece (10 Days)
- The Highlights of Greece & Italy - 15 Days (Self-guided)
- Explore the Imperial Forums in Rome
- Visit St. Peter's Basilica in the Vatican
- Tour the pink cathedral in Trani
Duration 16 days Destinations Rome, Trani, Bari, Brindisi, Igoumenitsa, Metsovo, Kalabaka, Delphi, Athens, RhodesSee all destinations Age Range up to 85 year olds Operated in English Operator Europamundo From $3,348
15% Off- US$2,846You save $502
Italy and Greece 4 Star w/Catamaran in Santorini
15 Reviews by TourRadar travelers“Wanderful holidays allowed us to make small customized changes to add an extra day.”
Megan, traveled in June 2024
- Ride a gondola through Venice's Grand Canal
- Explore St. Mark's Basilica and Bell Tower
- Tour the Colosseum, Roman Forum, and Palatine Hill
Duration 10 days Destinations Venice, Rome, Santorini, Athens Age Range up to 99 year olds Operated in English Operator Wanderful Holidays LLC From $2,899
4% Off- US$2,783You save $115
- Explore Athens with a local guide
- Visit the Meteora monasteries
- Tour the ancient ruins of Delphi
Duration 16 days Destinations Athens, Plaka, Kamena Vourla, Thermopylae, Kalabaka, Kastraki, Delphi, Corinth, Aegina, PorosSee all destinations Age Range up to 85 year olds Operated in English Operator Europamundo From $2,683
15% Off- US$2,281You save $402
Best of Italy and Greece with 3-day cruise
2 Reviews by TourRadar travelers“The customer service was impeccable. The tours were fabulous and the itinerary perfect.”
Michele, traveled in April 2024
- Explore the iconic Colosseum with a guide
- Visit St. Francis Basilica in medieval Assisi
- Discover Florence, the Cradle of Renaissance
Duration 12 days Destinations Italy, Greece, Turkey Age Range 6 to 80 year olds Operated in English, Spanish Operator Eskapas From $3,905
3% Off- US$3,788+$205 upfront costsYou save $117
- Explore Athens with a local guide
- Visit the ancient Olympia Archaeological Site
- Tour Alberobello's unique trulli houses
Duration 12 days Destinations Greece, Italy, Vatican City (Holy See) Age Range up to 85 year olds Operated in English Operator Europamundo From $2,269
15% Off- US$1,929You save $340
Italy and Greece Highlights with Island Hopping
5 Reviews by TourRadar travelers“I've gained new friends that I will keep for a lifetime! All the hotels we stayed in were decent to very nice.”
Daniel, traveled in August 2024
- Explore Rome's iconic fountains at night
- Visit the Sistine Chapel and Vatican Museums
- Enjoy a spritz and cicchetti in Venice
Duration 16 days Destinations Rome, Assisi, Siena, Florence, Bologna, Padua, Mestre, Venice, Montepulciano, AthensSee all destinations Age Range 6 to 90 year olds Operated in English, Spanish Operator Eskapas From $4,675
3% Off- US$4,535You save $140
Best of Italy and Greece (14 Days)
8 Reviews by TourRadar travelers“Accommodations were great, food was excellent, and the travel was very well organized.”
Perry, traveled in September 2023
- Discover the world of Ancient Greeks and Romans
- Weave through the picturesque Greek Islands on a boat
- Gaze in awe at the magical monasteries of Meteora
Duration 14 days Destinations Italy, Greece, Turkey Age Range up to 99 year olds Operated in English Operator Trafalgar From
3% Off- US$6,018
- Ride a gondola through Venice's iconic canals
- Explore the historic Roman Forum and Colosseum
- Discover the colorful islands of Murano and Burano
Duration 11 days Destinations Venice, Rome, Naples, Santorini Age Range 2 to 89 year olds Operated in English Operator Wanderful Holidays LLC From $2,999
4% Off- US$2,879You save $119
Best of Italy and Greece (10 Days)
8 Reviews by TourRadar travelers“The hotels were clean and comfortable. The coaches were also comfortable.”
Becky, traveled in June 2023
- Discover the world of Ancient Greeks and Romans
- Venture to Greece onboard an overnight ferry
- Gaze in awe at the magical monasteries of Meteora
Duration 10 days Destinations Italy, Vatican City (Holy See), Greece Age Range up to 99 year olds Operated in English Operator Trafalgar From
4% Off- US$4,418
The Highlights of Greece & Italy - 15 Days (Self-guided)
10 Reviews by TourRadar travelers“It was nice to have all the accomodations and (most) travel items looked after, along with a couple activites.”
Emma, traveled in October 2024
- Visit the impressive Acropolis
- Watch Whitewashed Mykonos
- Catch a Santorini Sunset
Duration 15 days Destinations Athens, Mykonos, Santorini, Rome, Pisa, Florence, Venice Age Range up to 99 year olds Operated in English, German, French, Dutch Operator Dot Travel From $3,907
20% Off- US$3,126You save $781
