Fully Guided Tours & Trips in Midwest USA
4.5 stars on(7,178 reviews)- Choose from 6 Midwest USA tours
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6 best fully guided Midwest USA tours
Compiled by
MelissaMidwest USA travel expert at TourRadar
- Mackinac Island & the Great Lakes
- Mackinac Island (Chicago, IL to Southfield, MI) (2025)
- Mackinac Island featuring the Tulip Time Festival (Chicago, IL to Southfield, MI) (2025)
- Route 66 (7 nights) from Chicago/to Albuquerque
- Route 66 (14 nights) from Chicago/to Los Angeles
- America's Heartland St. Louis, Missouri (Alton) to St Paul, Minnesota
Mackinac Island & the Great Lakes
120 Reviews by TourRadar travelers“Great destination tour - was not disappointed.”
Susan, traveled in September 2023
- Explore the Henry Ford Museum
- Enjoy Bavarian cuisine in Frankenmuth
- Ride a carriage on Mackinac Island
Duration 8 days Destinations Detroit, Frankenmuth, Mackinac Island, Charlevoix, Petoskey, Sleeping Bear Dunes National Lakeshore, Grand Rapids, Chicago Age Range up to 80 year olds Operated in English Operator Globus From $3,969
13% Off- US$3,469You save $500
- Explore Chicago's iconic architecture
- Tour Mackinac Island by horse-drawn carriage
- Relax at the historic Grand Hotel's porch
Duration 9 days Destinations Chicago, Grand Rapids, Mackinac Island, Frankenmuth, Southfield, Dearborn Age Range 5 to 99 year olds Operated in English Operator Collette From $3,399
10% Off- US$3,059You save $339
Mackinac Island featuring the Tulip Time Festival (Chicago, IL to Southfield, MI) (2025)
29 Reviews by TourRadar travelers
- Explore Chicago's iconic architecture
- Celebrate at Holland's Tulip Time Festival
- Stay at Mackinac Island's Grand Hotel
Duration 9 days Destinations Chicago, Mackinac Island, Holland, Grand Rapids, Frankenmuth, Southfield, Dearborn Age Range up to 99 year olds Operated in English Operator Collette From $3,799
10% Off- US$3,419You save $379
Duration 8 days Destinations Chicago, Springfield, Pontiac, St. Louis Age Range 21 to 99 year olds Operated in Only: German Operator DERTOUR From
10% Off- US$2,750
Duration 15 days Destinations Chicago, Springfield, Pontiac, St. Louis Age Range 21 to 99 year olds Operated in Only: German Operator DERTOUR From
10% Off- US$4,973
- Explore St. Louis' architectural gems
- Relive Twain's tales in Hannibal
- Tour Burlington's historic downtown
No departure dates availableDuration 8 days Destinations St. Louis, Hannibal, Dubuque, La Crosse, Red Wing, Saint Paul Age Range up to 90 year olds Operated in English Operator Viking Cruises
